TOPS
Principal Investigator:
Stephen P. Messier, PhD
Objective:
The objective of this Phase III, multi-site (Boston, MA, Chapel Hill, NC, Sydney, Australia, and Winston-Salem, NC) randomized clinical trial is to establish the efficacy of an intervention of dietary weight loss, exercise, and weight-loss maintenance for knee OA prevention.
Site Principal Investigators:
Site PI: Shannon Mihalko, PhD
Site PI: Elena Losina, PhD, MSc
Site PI: Leigh Callahan, PhD
Data Coordinating Center: Edward Ip, PhD
Site PI: David Hunter, MD
Data Coordinating Center: Jimi Cook, DVM, PhD, OTSC
Co-Investigators:
Ali Guermazi, MD, PhD, Jeffery Katz, MD, MSc, Emily Leary, PhD, Richard Loeser Jr., MD, Gary Miller, R.D. PhD, Brian Pietrosimone, PhD, ATC, Sandra Soto, PhD, Kurt Spindler, MD, Ezequiel Zamora, MD
Interested in Participating?
Study participants receive, at no cost:
- A 48-month healthy lifestyle program
- Classes may include a combination of weight loss, healthy lifestyle, nutrition, and exercise
You may qualify to participate if you:
- Are female and at least 50 years of age
- Are overweight
- Have little to no knee pain
Contact us:
To learn more, please call 877-238-4825, option 6; email us at tops@wfu.edu;
or visit https://redcap.link/jp42mvpo to see if you qualify